Fig. 2: Longitudinal logarithmic levels of serum Neurofilament light (NfL) in relation to gestational age, AA, and DHA.
From: Neurofilament light chain associates with IVH and ROP in extremely preterm infants
a Longitudinal NfL levels illustrated by lines and colors per gestational age group. Lines illustrate the mean concentrations with 95% CIs for each group based on gestational age; shaded areas show the postnatal period with significant differences between groups (yellow, 22–24 vs. 27 weeks GA; pink, 22–24 vs. 25–26 weeks GA). References for healthy infants at one year of age based on Schjørringet al. (2023). The relation to (b) docosahexaenoic acid (DHA) and (c) arachidonic acid (AA) levels are illustrated in the scatterplots for concentrations at postnatal days 14 (n = 119) and 28 (n = 149) and for mean daily levels during the first month (n = 162). P-values were adjusted for gestational age and intervention group. Abbreviations: AA arachidonic acid, CI Confidence interval, DHA docosahexaenoic acid, GA gestational age, NfL neurofilament light chain.
