Table 3 Multilevel linear mixed-effects models showing associations of VP children’s LD with SDQ total scores at age 5 years.

From: Associations of language barriers with very preterm children’s behavioural and socio-emotional problems across Europe

Dependent variable:

SDQ total score

 

Model 1 (N = 3067)

Model 2 (N = 3067)

Model 3 (N = 3020)

Model 4 (N = 2915)

Fixed effects, coefficient (95% confidence interval)

 LD

0.02 (0.02, 0.03)***

0.02 (0.01, 0.03)***

0.02 (0.01, 0.03)***

0.02 (0.01, 0.03)***

 Mother foreign country of birth

0.63 (0.16, 1.10)**

0.40 (−0.26, 1.07)

0.15 (−0.61, 0.92)

0.24 (−0.44, 0.92)

 Mother’s education (high vs. low)

  

−1.45 (−2.26, −0.64)***

−1.43 (−2.27, −0.59)***

 Single mother

  

−0.62 (−1.28, 0.04)

−0.60 (−1.14, −0.06)*

 Household unemployment

  

1.73 (0.57, 2.90)**

1.45 (0.47, 2.42)**

 Gestational age (weeks)

   

−0.08 (−0.19, 0.04)

 Biological sex (female vs. male)

   

−1.53 (−2.01, −1.05)***

 Multiple birth

   

−0.94 (−1.32, −0.56)***

 Parity (multi- vs. primiparous)

   

−0.59 (−1.02, −0.16)**

 Severe neonatal morbiditya

   

1.25 (0.32, 2.18)**

 BPDb

   

1.01 (−0.34, 2.37)

 Mother’s age (years)

   

−0.05 (−0.07, −0.02)**

 constant

 

8.88 (7.54, 10.22)***

10.79 (8.64, 12.94)***

15.11 (11.53, 18.70)***

Random effects by family

 SD (constant)

 

5.17 (4.83, 5.53)*

5.09 (4.75, 5.45)*

4.97 (4.63, 5.33)*

Random effects by country

 SD (constant)

 

1.32 (0.96, 1.82)*

2.15 (1.83, 2.53)*

1.24 (0.86, 1.79)*

Log-pseudolikelihood

 

−14,827.37

−14,568.20

−13,852.13

  1. LD linguistic distance, VP very preterm, SDQ Strengths and Difficulties Questionnaire, SD standard deviation, BPD bronchopulmonary dysplasia. Model 1 = unadjusted; Model 2 = LD and immigrant status adjusted for each other; Model 3 = additionally adjusted for mothers’ education, single mother status, household unemployment; Model 4 = fully adjusted, including LD, immigrant status, mothers’ education, single mother status, household unemployment, child GA, sex, multiple birth, mothers’ age, parity, BPD, severe neonatal morbidity; all models adjusted for IPW; for fixed effects *p < 0.05; **p ≤ 0.01; ***p ≤ 0.001; for random effects * marks a 95% confidence interval not including 0; significant effects of interest marked in bold;
  2. aSevere neonatal morbidity defined as a composite measure of cystic periventricular leukomalacia, intraventricular haemorrhage grades III or IV, severe necrotizing enterocolitis requiring surgery or peritoneal drainage, or retinopathy of prematurity at least stage 3;
  3. bBPD = Bronchopulmonary dysplasia with supplemental oxygen and/or ventilatory support (continuous positive airway pressure or mechanical ventilation) at 36 weeks of postmenstrual age.