Fig. 1: The monthly distribution of acute SARS-CoV-2 infection in the study population.

The presence of SARS-CoV-2 in patients with long COVID syndrome (LCS) and in the control group was proved with PCR, rapid antigen test, or after the acute infection with antibody tests (anti-spike or anti-nucleocapsid ELISA). The x axis shows the timeline of the pandemic by month, and the y-axis shows the number of participants (LCS: 124, CG+: 20). The waves of COVID-19 in Hungary (elevation in the number of new cases/day) are indicated roughly. The third wave was dominated by the Alpha strain, the fourth by the Delta, and the fifth by the Omicron variant.