Table 1 Target genes regulating surfactant maturation and lipid transport, fetal lung liquid movement, glucocorticoid signaling and hypoxia signaling by quantitative real-time RT-PCR (all primer sequences and concentrations previously published⁴⁴).

 Surfactant protein

SFTP-A

SFTP-B

SFTP-C

SFTP-D

SP-A

SP-B

SP-C

SP-D

Pulmonary immunity and surface tension regulating

 Phosphate cytidylyltransferase 1, choline, alpha

PCYT1A

PCYT1A

Surfactant lipid synthesis

 Cystic fibrosis transmembrane conductance regulator

CFTR

CFTR

Chloride movement

 Chloride channel voltage-sensitive 2 channel

CLCN2

CLCN2

Chloride movement

 Epithelial sodium channel subunits

SCNN1-A

SCNN1-B

SCNN1-G

ENAC-α

ENAC-β

ENAC-γ

Sodium movement

 Sodium potassium adenosine triphosphatase subunits

ATP1-A1

ATP1-B1

Na-K-ATPase-α1

Na-K-ATPase-β1

Sodium movement

 Aquaporins

AQP-1

AQP-3

AQP-4

AQP-5

AQP-1

AQP-3

AQP-4

AQP-5

Water movement

 11β-hydroxysteroid dehydrogenase-1

HSD11B-1

11βHSD-1

Glucocorticoid activating enzyme isoform

 11β-hydroxysteroid dehydrogenase-2

HSD11B-2

11βHSD-2

Glucorticoid de-activating enzyme isoform

 Glucocorticoid receptor

NR3C1

GR

Cellular glucocorticoid receptor

 NK2 homeobox 1 - thyroid transcription factor

NKX2-1

TTF-1

Glucorticoid responsive gene

 Hypoxia inducible factor subunits

HIF-1α

HIF-2α

HIF-3α

HIF-1b

HIF-1α

HIF-2α

HIF-3α

HIF-1β

Major regulators of hypoxia signalling

 Egl-9 family hypoxia-inducible factor enzymes (encoding the prolyl hydroxylase domain proteins)

EGLN-1

EGLN-2

EGLN-3

PHD-2

PHD-1

PHD-3

Regulator of HIF activity and signaling

 Vascular endothelial growth factor

VEGF

VEGF

Hypoxia responsive gene

 Adrenomedullin

ADM

ADM

Hypoxia responsive gene

 Lysine (K)-specific demethylase 3 A

KDM3A

JMJD1A

Hypoxia responsive gene

 Solute carrier family 2, Facilitated glucose transporter member-1

SLC2A1

GLUT-1

Hypoxia responsive gene