Table 1 Demographic and clinical characteristics of the study population used in the training dataset.
Severe BPD (n = 149) | No severe BPD (n = 1251) | p-value | |
|---|---|---|---|
Gestational age (week) | 25.4 (23.7–27.6) | 29.4 (27.2–31.0) | <0.0001 |
Birth weight (g) | 712 (545–925) | 1148 (861–1372) | <0.0001 |
Birth weight (SDS) | −0.5 ( − 1.2–0.3) | −0.64 ( − 1.7–0.1) | 0.0779 |
Body length at birth (cm) | 31.3 (28.7–34.7) | 37.0 (33.8–39.5) | <0.0001 |
Body length at birth (SDS) | −0.43 ( − 1.3–0.2) | −0.49 ( − 1.4–0.3) | 0.9707 |
Male (n,%) | 77 (51.7) | 625 (50.0) | 0.6918 |
Clinical CAM (n,%) | 41 (27.7) | 145 (11.8) | <0.0001 |
Histologic CAM (n,%) | 67 (47.2) | 308 (25.9) | <0.0001 |
PROM (n,%) | 57 (38.8) | 338 (28.5) | 0.0099 |
Maternal steroid (n, %) | 90 (63.8) | 771 (64.0) | 0.9614 |
1 min Apgar score | 3 (1–5) | 5 (3–7) | <0.0001 |
5 min Apgar score | 6 (4–8) | 8 (6–9) | <0.0001 |
RDS (n,%) | 111 (74.5) | 741 (59.4) | 0.0003 |
Pulmonary hemorrhage (n,%) | 4 (2.68) | 14 (1.13) | 0.1116 |
Symptomatic PDA (n,%) | 73 (49.3) | 433 (35.6) | 0.0011 |
IVH (n,%) | 33 (22.5) | 147 (12.1) | 0.0005 |
Sepsis (n,%) | 22 (14.97) | 60 (4.94) | <0.0001 |
Intubation at birth (n,%) | 130 (87.2) | 880 (71.2) | <0.0001 |
RS score (day7) | 1.89 (1.31 − 2.65) | 1.26 (0.84–1.45) | <0.0001 |
RS score (day14) | 2.20 (1.43 − 3.81) | 1.05 (0.0–1.43) | <0.0001 |
Inhaled corticosteroid (n,%) | 72 (48.3) | 213 (17.7) | <0.0001 |
Systemic corticosteroid (n,%) | 79 (55.6) | 154 (19.47) | <0.0001 |
HFO (n,%) | 88 (64.2) | 257 (25.8) | <0.0001 |
Length of Invasive ventilation (day) | 43 (4–68) | 2 (1–12) | <0.0001 |
Length of Noninvasive ventilation (day) | 39 (16 − 59) | 27 (10–41) | <0.0001 |
Age at discharge (day) | 137 (104–168) | 73 (54–100) | <0.0001 |
