Table 4 Scoring system as defined by Alarcón et al. for assessing cCMV neuroimaging abnormalities.104

From: Beyond hearing loss: exploring neurological and neurodevelopmental sequelae in asymptomatic congenital cytomegalovirus infection

Score

Description

0

None of the following abnormalities.

1

Single punctate periventricular calcification, lenticulostriate vasculopathy, caudothalamic germinolysis, ventriculomegaly (excluding severe)a and focal/multifocal white matter signal abnormalities on MRI.

2

Multiple discrete periventricular calcifications, paraventricular germinolytic cysts, severe ventriculomegaly, diffuse white matter signal abnormalities and/or temporal lobe involvement.

3

Extensive calcifications, brain atrophy, abnormal gyration, cortical malformation, dysgenesis of the corpus callosum and/or cerebellar hypoplasia.

  1. aVentriculomegaly was defined as ventricular index exceeding the 97th centile for gestational age and considered severe when the ventricular index surpassed the 97th centile plus 4 mm.
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