Fig. 1: Relative expression of circulating miRNAs in pediatric gliomas.
From: Circulating miRNAs as potential liquid biomarkers for pediatric gliomas
The relative plasma expression levels of mir-182-5p, mir-25-3p, mir-10b-5p, mir-106b-3p, and mir-21-5p, are presented for Healthy control individuals and Glioma patients. a (p < 0.01); b (p < 0.001); c (p < 0.005); d, e present HCs compared to Total glioma patients (statistical analysis with t test), while in (f–j) present the circulating expression of each miRNA is presented separately, for the different pediatric glioma group: pediatric LGG, Optic Glioma, LGG + NF1 germline mutations (LGG.NF1), LGG + FGFR Aberrations (LGG.FGFR), Brain Stem and spinal cord LGGs (BS&SC. LGGs), and for HGGs Brain Stem and pHGG-IV (HGG). The results are presented in Relative quantities (Rq = 2−ΔΔCt).
