Fig. 3: ROC plot visualizing the diagnostic performance of cTnT and NT-proBNP.
From: Cardiotoxicity in pediatric oncology: a systematic review and meta-analysis
cTnT cardiac troponin T, HSROC hierarchical summary receiver operating characteristic curve, NT-proBNP N-terminal pro-B-type natriuretic peptide. This figure displays the summary ROC curve and sensitivity/specificity estimates from five studies26,27,28,29,30 for cardiac biomarkers used to detect cardiotoxicity. The pooled analysis indicates that NT-proBNP has moderate accuracy, while troponin T is more consistent but less sensitive, with performance strongly influenced by measurement timing and thresholds.
