Table 2 Laboratory investigations of the studied groups

From: Pediatric community-acquired pneumonia: predictive value of heparin-binding protein for severity assessment

 

Simple pneumonia (N = 30)

Severe pneumonia (N = 60)

Test of sig.

P value

Hb (gm/dL)

Mean ± SD

11.97 ± 1.39

10.22 ± 1.14

t = 313.50

<0.001*

Platelets (*109/L)

Mean ± SD

282.33 ± 36.38

371.62 ± 166.89

t = 530.50

0.005*

WBCs (*109/L)

Mean ± SD

6.62 ± 1.18

13.25 ± 5.79

t = 145.00

<0.001*

CRP (mg/L)

Median (IQR)

1.7 (1.4 - 2.2)

24 (12–48)

U = 0.000

<0.001*

ALT (U/L)

Median (IQR)

21(19-23)

22(20-32.25)

U = 614.0

0.014*

AST (U/L)

Median (IQR)

20 (18 – 22)

24 (18–34.5)

U = 642.50

0.028*

Albumin (g/dL)

Mean ± SD

3.95 ± 0.38

3.61 ± 0.22

t = 5.427

<0.001*

Creatinine (mg/dL)

Mean ± SD

0.46 ± 0.05

0.52 ± 0.3

t = 1.124

0.264

Urea (mg/dL)

Mean ± SD

12.97 ± 3.18

20.82 ± 8.09

t = 5.111

0.028*

Na (mEq/L)

Mean ± SD

138.93 ± 2.16

136.41 ± 3.02

t = 4.071

<0.001*

K (mEq/L)

Mean ± SD

4.07 ± 0.36

4.27 ± 0.7

t = 1.457

0.149

Ca (mg/dL)

Mean ± SD

9.78 ± 0.45

9.06 ± 0.55

t = 6.195

<0.001*

pH

Mean ± SD

7.4 ± 0.03

7.38 ± 0.08

t = 1.197

0.234

CO2 (mmol/L)

Mean ± SD

35.93 ± 2.02

41.25 ± 13.08

t = 2.207

0.030*

HCO3 (mEq/L)

Mean ± SD

25.27 ± 2.07

20.43 ± 4.56

t = 5.525

<0.001*

HBP(ng/ml)

Mean ± SD

0.73 ± 0.21

7.87 ± 1.04

t = 37.060

<0.001*

Blood Culture (N %)

Positive Negative

0 (0%)

30 (100%)

13(21.7%)

47(78.3%)

X2 = 5.82

0.02*

Radiological finding (N %)

Lobar pneumonia

11(36.67%)

12(20%)

X2 = 2.92

0.087

Patchy pneumonia

19(63.33%)

48(80%)

  1. IQR interquartile range, SD standard deviation, Hb hemoglobin, WBCs white blood cells, CRP C-reactive protein, ALT alanine aminotransferase, AST aspartate aminotransferase, Na Sodium, K Potassium, Ca Calcium, CO2 carbon Dioxide, HCO3 bicarbonate, HBP Heparin binding protein, U Mann–Whitney U test, t independent- samples t test, X2 chi-square test, * statistically significant.
  2. Statistically significant p-values are in bold.