Table 1 Maternal and neonatal characteristics in HIE cohort.

From: Multiorgan impact of neonatal encephalopathy: higher burden in preterm infants

Characteristics

Preterm (N = 54)

Full-term (N = 452)

P-Value

Maternal

Maternal age (years)

30 [26 34]

27 [22 33]

0.090

Gravidity

4 [2, 4]

2 [1, 4]

<0.001

Parity

2 [1, 2]

1 [0, 2]

<0.001

Route of Delivery, N. (%)

  

0.002

  Vaginal

5 (9)

135 (30)

 

  C-section

49 (91)

315 (70)

 

Prenatal care, N. (%)

51 (94)

430 (96)

0.447

Clinical Chorioamnionitis, N. (%)

5 (9)

108 (26)

<0.001

Neonatal

Race, N. (%)

  

0.322

  White

36 (67)

334 (75)

 

  Black

17 (31)

96 (22)

 

  Asian

1 (2)

13 (3)

 

Ethnicity, N. (%)

  

0.303

  Non-Hispanic

20 (37)

134 (30)

 

  Hispanic

34 (63)

310 (69)

 

Sex, N. (%)

  

0.748

  Male

29 (54)

252 (56)

 

  Female

25 (46)

198 (44)

 

Gestational age (weeks)

32 [30, 33]

39 [38, 40]

-

Birth weight (grams)

1747 ± 521

3262 ± 620

-

Apgar 1 min

1 [0, 2]

2 [1, 4]

<0.001

Apgar 5 min

4 [2, 6]

6 [3, 7]

<0.001

Apgar 10 min

5 [3, 7]

6 [4, 8]

0.001

Blood gas pH at birth

7.1 [6.8 7.3]

7.0 [6.9 7.1]

0.073

Blood gas Base Deficit at birth

13 [6, 25]

17 [13, 22]

0.048

Seizures during hospital stay, N.(%)

19 (35)

72 (16)

<0.001

Total hospital days

35 [23, 65]

12 [7, 22]

<0.001

Death, N. (%)

10 (18)

30 (7)

0.006

  1. Continuous variables were compared using Student’s t-test or the Wilcoxon rank-sum test, and categorical variables using the chi-square (χ²) test or Fisher’s exact test; when normality was violated, data were summarized as median (IQR) and analyzed with the Wilcoxon rank-sum test.