Table 1 Components of CPAP practice before and after the implementation of the new guidelines.

From: Structured implementation of a bubble-CPAP program to reduce bronchopulmonary dysplasia in preterm infants

Element

Baseline CPAP practice

New b-CPAP guidelines

Delivery room management

Preterm infants are intubated, and surfactant is administered shortly after

CPAP is the primary mode of support. Preterm infants are intubated if they have apnea or if unable to achieve goal saturation while supported with CPAP

CPAP device

Machine generated via ventilators, infant flow apparatus, or biphasic CPAP device

Only bubble CPAP

Facial interface

Facial mask, binasal prongs, or RAM cannula

Only short curved binasal prongs

CPAP pressure

No limits; ranging from 4 to 12 cmH2O

5 cmH2O with the option to increase to 6 cmH2O if no improvement

CPAP failure criteria

Unspecified

FiO2 > 50% in the first day or >60% thereafter, clinically significant apnea, and PCO2 > 65 mmHg accompanied with metabolic acidosis (BD > 10 mmol/L)

CPAP weaning criteria

Unspecified- frequent transition HFNC

Weaning of FiO2 until reaches 21%. No use of HFNC. No pressure wean. CPAP is tried off once a day until successful.

CPAP exchange with nasal cannula or HFNC

Yes

Not permitted

Respiratory support after extubation

NIPPV, CPAP, HFNC

Bubble CPAP

CPAP implementation tool

  

 Bedside CPAP training

No

Yes

 Bedside checklist

No

Yes

 CPAP guidelines

No

Yes

 Reliability measure

No

Yes

  1. b-CPAP bubble CPAP, BD base deficit, CPAP continuous positive airway pressure, DR delivery room, FiO2 fraction of inspired oxygen, HFNC high flow nasal cannula, NICU neonatal intensive care nursery, NIPPV non-invasive positive pressure ventilation, PCO2 partial pressure of carbon dioxide.