Fig. 4: Changes in the alpha-diversity of the gut microbiota before and after the administration of antibiotics or PBS to PAN rats. | Pediatric Research

Fig. 4: Changes in the alpha-diversity of the gut microbiota before and after the administration of antibiotics or PBS to PAN rats.

From: Depletion of gut microbiota alleviates proteinuria in puromycin aminonucleoside-induced nephrosis in rats

Fig. 4

a Observed features of the gut microbiota. b The Shannon index of the gut microbiota. Observed features of the gut microbiota indicating the number of observed species did not change significantly before and after PBS administration (p = 0.72), but were significantly decreased after 10 days of antibiotic administration (p = 0.0014). Similarly, Shannon index, which indicates the abundance and homogeneity of bacterial species, showed no significant change before and after PBS administration (p = 0.78), but was significantly lower after 10 days of antibiotic administration (p = 0.0028). PBS phosphate-buffered saline, PAN puromycin aminonucleoside.

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