Fig. 6 | Signal Transduction and Targeted Therapy

Fig. 6

From: Potent delivery of an MMP inhibitor to the tumor microenvironment with thermosensitive liposomes for the suppression of metastasis and angiogenesis

Fig. 6

MMP inhibition in vivo. a Western blot analysis of MMP-2 and MMP-9 expression in tumors. b The activity of MMP-2 and MMP-9 measured by gelatin zymography. c Quantitative analysis of MMP activity from zymograms using a computer analysis program. Quantitative analysis of d MMP-2 and e MMP-9 expression. Glyceraldehyde 3-phosphate dehydrogenase (GADPH) was used as a loading control. Tumors used in these experiments were collected from 4T1 tumor-bearing Balb/C mice on day 19 after treatment (mean ± SD, n = 3, *p < 0.05)

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