Table 1 Concentrations (mean ± SD) of Trp and Kyn and the Kyn/Trp ratio in the supernatant of THP-M

From: The proatherosclerotic function of indoleamine 2, 3-dioxygenase 1 in the developmental stage of atherosclerosis

 

Blank

oxLDL

IFN-γ

IFN-γ+oxLDL

oxLDL+IFN-γ

Trp (μmol/L)

41.58 ± 10.56

31.27 ± 13.28

23.92 ± 9.92

16.62 ± 10.91

23.04 ± 5.66

Kyn (μmol/L)

2.40 ± 1.14

2.91 ± 0.15

4.31 ± 2.50

10.93 ± 7.77

10.67 ± 1.84

(Kyn/Trp) × 100

5.54 ± 1.60

11.28 ± 6.96

17.12 ± 5.32

66.12 ± 34.76*

50.11 ± 23.17

  1. Data were based on at least three independent experiments
  2. *p < 0.05
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