Fig. 2 | Signal Transduction and Targeted Therapy

Fig. 2

From: Overcoming cancer therapeutic bottleneck by drug repurposing

Fig. 2The alternative text for this image may have been generated using AI.

Identification of drug candidates targeting the hallmarks of the cancer cell using drug repurposing enabled by recapitulative signaling networks. The complex signaling interactions contributing to the hallmarks of cancer cells can be orchestrated, rationalizing the complexities of neoplastic disease. Drug candidates interfering with cancer capabilities are shown. CAFs cancer-associated fibroblasts, CTLs cytotoxic T lymphocytes, ECM extracellular matrix, MDSCs myeloid-derived suppressor cells, NK cells natural killer cells, Tregs regulatory T cells

Back to article page