Fig. 5
From: The potent roles of salt-inducible kinases (SIKs) in metabolic homeostasis and tumorigenesis
Potential inhibitors targeting SIKs. SIK inhibitors are divided into selective and non-selective inhibitors. HG-9-91-01, YKL-05-099, MRT-199665, YKL-06-061, and YKL-06-062 are all selective pan-SIK inhibitors. ARN-3236 and pterosin B inhibit SIK2 and SIK3, respectively. Dasatinib, bosutinib, staurosporine, diosmetin, crenolanib and MRT-67307 have non-selective inhibitory effects on SIKs by targeting different kianses labled as below
