Fig. 1
From: COVID-19-activated SREBP2 disturbs cholesterol biosynthesis and leads to cytokine storm
Analysis of patients’ blood revealed the SREBP-2 as a severity diagnostic marker for COVID-19. a Activation level of SREBP-2 with respect to the severity of COVID-19 (**p < 0.01). b Activation level of SREBP-2 in survival and deceased patients of COVID-19 (**p < 0.01). c Activation level of NF-κB with respect to the severity of COVID-19 (**p < 0.01). d Activation level of NF-κB in survival and deceased patients of COVID-19 (**p < 0.01). e Level of IL-1β in the COVID-19 patients’ plasma (**p < 0.01). f Level of TNF-α in the COVID-19 patients’ plasma (**p < 0.01). g Relative viability of PBMCs obtained from COVID-19 patients with respect to the culture time in vitro (**p < 0.01). h Activation level of SREBP-2 in PBMCs obtained from COVID-19 patients (**p < 0.01, n.s. not significant)
