Fig. 2
From: Regulation of cardiomyocyte fate plasticity: a key strategy for cardiac regeneration
Physiological and pathological factors involved in the regulation of cardiomyocyte proliferation. a Comparison of embryonic development and post-natal cardiac microenvironment (oxygenated state) on cell proliferation potential. b Under stress or injury, the changes in pathological microenvironment play a vital role in heart repair and cardiac regeneration. CMs cardiomyocytes, ECM extracellular matrix, ROS reactive oxygen species. ↑: upregulate, (+): promote, (-): inhibit
