Fig. 4
From: Regulation of cardiomyocyte fate plasticity: a key strategy for cardiac regeneration
The vital regulatory roles of non-coding RNAs in cardiac regeneration after injury. MiRNAs regulate the critical process of heart repair and subsequent remodeling after infarction. Among them, miRNA (miR-34 family, miR-15 family, and miR-17-92 cluster), lncRNA (LncCAREL) and circRNA (CircNfix) negatively regulate the proliferation of cardiomyocytes. CircRNAs also play a critical role in controlling cardiomyocyte proliferation, angiogenesis and even tissue regeneration. CMs cardiomyocytes, CircRNA circular RNA, LncRNA long non-coding RNA, miRNAs microRNAs. (-): inhibit
