Table 4 ncRNAs influence TIE via regulate EMT by targeting EMT- related transcription factors

miR-543, 300, 186, 137, 720, 580, 539, 33a, 33b, 520d-5p, 106b, 675,337-3p and 151-5p

Inhibit EMT of tumor cells by targeting and downregulating Twist1, an EMT related transcription factor

Endometrial cancer, Epithelial ovarian cancer, Gastrointestinal stromal tumor, Breast cancer, Osteosarcoma, Melanoma, endometrial carcinoma, HCC, Lung carcinoma

^{120,406,407,408,409,410,411,412,413,414,415,416,417}

miR-23a, lncRNA AK027294, lncRNA ROR and lncRNA AFAP1-AS1

Promote EMT of tumor cells by targeting and upregulating Twist1, an EMT related transcription factor

Tongue squamous cell carcinoma, Colorectal cancer, Gallbladder cancer

^{121,418,419,420}

miR-21, 137, 34a, 491-5p, 22, 363, 30, 145, 153, 410-3p

Target and downregulate transcription factor Snail, and then inhibit EMT of tumor cells

Colorectal cancer, Ovarian cancer, Gastric cancer, Bladder cancer, Lung cancer, Osteosarcoma, HCC, Breast cancer

^{117,118,421,422,423,424,425,426,427}

miR-106a, circRNA 0084043, circRNA PRMT5, lncRNA PVT1 and lncRNA UCA1

Target and upregulate transcription factor Snail, and then promote EMT of tumor cells

Glioma, Melanoma, Bladder carcinoma, Pancreatic cancer, Breast cancer

^{119,122,124,428,429}

miR-203, 873, 205-5p, 5702, 126, 186-5p

Target and downregulate transcription factor ZEB1, and then inhibit EMT of tumor cells

Gastric cancer, Breast cancer, Prostate cancer, NSCLC, Cervical cancer, Colorectal cancer

^{430,431,432,433,434,435}

lncRNA MALAT1, ZEB1-AS1, SNHG16, NNT-AS1, HOTTIP, NEAT1, ZNF469-3, TP73-AS1, circRNA TSPAN4 and circRNA PVT1

Target and upregulate transcription factor ZEB1, and then promote EMT of tumor cells

HCC, NSCLC, Osteosarcoma, Breast cancer, Glioma, Nasopharyngeal carcinoma, Lung adenocarcinoma, Gastric cancer

^{436,437,438,439,440,441,442,443,444,445}