Fig. 2
From: Differential immune responses in pregnant patients recovered from COVID-19
Pregnancy-associated immunity impact on anti-SARS-CoV-2 responses. a Heatmap of differentially expressed genes identified from pseudo-bulk gene analysis. The color scale indicates Z score-transformed expression level. b The UMAP projection of 17 donors based on the pseudo-bulk gene expression matrix presented in a. Samples were colored and shaded according to their assigned groups. Blue, pregnant patients who developed mild symptoms (PCovM); red, pregnant patient who developed severe symptoms (PCovS); green, non-pregnant patients who developed mild symptoms (NCovM); orange, non-pregnant patients who developed severe symptoms or had prolonged viral shedding (NCovS). c Upregulated or downregulated differentially expressed genes (DEGs) in each cell type of recovered COVID-19 patients compared to their corresponding healthy controls (PCovM and PCovS compared to PHC; NCovM and NCovS compared to NHC). Prioritizing the most affected cell types in response to COVID-19 (d) or pregnancy (e) by ranking the AUC scores derived from Augur algorithm43
