Fig. 1: Single-cell RNA sequencing of peripheral blood cells from COVID-19 patients.
From: Single-cell immune profiling reveals distinct immune response in asymptomatic COVID-19 patients
a Timeline of blood sample collection in the 19 subjects (seven asymptomatic, eight moderate, one severe patient, and three healthy controls) and schematic outline of the study design. The days were recorded based on the time after symptom onset for moderate and severe patients and the first positive RT-PCR test for SARS-CoV-2 for asymptomatic patients. b Bar plot shows the log10 transformed cell number of each sample for each subject at different time points. Green, orange, blue, and red represent samples collected from healthy controls, asymptomatic, moderate, and severe patients, respectively. The same color palette was used throughout the study. c Cell type UMAP representation of all merged samples. Sixteen cell types were identified by cluster gene signatures and color-coded. Each dot represents an individual cell. d Canonical cell markers that are used to annotate clusters as represented in the UMAP plot. Colored according to expression levels and legend labeled in log scale. e Dot plots of average expression and percentage of expressed cells of marker genes in each labeled cell type
