Fig. 4

FNC protected lung from SARS-CoV-2 infection. a left. FNC reduced petechial spots (red circle) in lung of virus (+) monkeys. a right. Chest X-ray images clearly showed the ground-glass shadows or light shadows in the untreated monkeys (red circle), but much less in the FNC-treated virus (+) monkeys. b HE staining of the lung tissues was done and evaluated. Lesions in the lung of the untreated virus (+) monkeys included interstitial infiltration of neutrocytes or monocytes or macrophage, thickening of alveolar septae and vessel wall, blood effusion, edema, and fibrin with hyaline membranes as well as damage in cell structures (see green arrows); treating the monkeys with FNC substantially reduced the lesion described above