Fig. 1 | Signal Transduction and Targeted Therapy

Fig. 1

From: Ionizable liposomal siRNA therapeutics enables potent and persistent treatment of Hepatitis B

Fig. 1

Characteristics of RBP131/siRNA nanoparticles. a Schematic illustration of RBP131/siRNA nanoparticle and the compositions. b Cryo-EM image of RBP131/siRNA nanoparticles. c Appearance of liquid and lyophilized RBP131/siRNA formulations. d–f Particle size (d), polydispersity index (PDI) (e), and encapsulation efficiency (f) changes when RBP131/siRNA was kept at −20 °C, 4 °C, 25 °C for 1, 2, 3 and 4 weeks, respectively. g Primary quality specifications of RBP131/siRNA formulation. h pKa titration of RBP131/siRNA complex

Back to article page