Table 1 Baseline demographic characteristics of the 143 NSCLC patients

From: Tobacco carcinogen induces tryptophan metabolism and immune suppression via induction of indoleamine 2,3-dioxygenase 1

Variable

No. of cases (%)

Trp/Kyn ratio

High, n (%)

Low, n (%)

P values*

Total

143

71 (49.7)

72 (50.3)

 

Age at diagnosis

   

0.025

 <60

72 (50.3)

43 (59.7)

29 (40.3)

 

 ≥60

70 (49)

27 (38.6)

43 (61.4)

 

 Unknown

1 (0.7)

1 (100)

0 (0)

 

Gender

   

0.303

 Male

74 (51.7)

33 (44.6)

41 (55.4)

 

 Female

68 (47.6)

37 (54.4)

31 (45.6)

 

 Unknown

1 (0.7)

1 (100)

0 (0)

 

Smoke status

   

0.002

 Smoker

72 (50.3)

26 (36.1)

46 (63.9)

 

 Nonsmoker

70 (49)

45 (64.3)

25 (35.7)

 

 Unknown

1 (0.7)

0 (0)

1 (100)

 

Histology

   

0.406

 LUAD

84 (58.7)

44 (52.4)

40 (47.6)

 

 LUSC

58 (40.6)

26 (44.8)

32 (55.2)

 

 Unknown

1 (0.7)

1 (100)

0 (0)

 

Stage

   

0.021

 I–II

49 (34.3)

30 (61.2)

19 (38.8)

 

 III–IV

65 (45.4)

24 (36.9)

41 (63.1)

 

 Unknown

29 (20.3)

17 (58.6)

12 (41.4)

 
  1. *P values were calculated using a two-sided Fisher’s exact test
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