Fig. 1 | Signal Transduction and Targeted Therapy

Fig. 1

From: The RING finger protein family in health and disease

Fig. 1

Classification of the RING finger (RNF) family. All members of the RNF family are characterized by the N-terminal RING domain. Each subfamily has its unique domains besides the conserved RING domain. The MARCH subfamily is characterized by the TM domain. The PA-TM-RING subfamily is characterized by the PA domain and two TM domains. The RBR subfamily is characterized by the IBR domain. The TRIM subfamily is characterized by two BB domains and a CC domain. The UIM subfamily is characterized by a C2HC-type zinc finger, two C2H2-type zinc fingers, and UIM

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