Fig. 6 | Signal Transduction and Targeted Therapy

Fig. 6

From: Deciphering transcriptome alterations in bone marrow hematopoiesis at single-cell resolution in immune thrombocytopenia

Fig. 6

Co-culture of immune cell progenitors and Mk-biased HSPCs. a Experimental strategy. Schematic illustration of the transwell co-culture systems. Related to Fig. 6. b, c The proportion of CD41a+CD61+ cells derived from CD9+LinCD34+CD45RA HSPCs co-cultured with pre-B cells of HC and ITP, respectively. Two-tailed Student’s t test; *p < 0.05; n = 5. d, e The proportion of CD41a+CD61+ cells derived from CD9+LinCD34+CD45RA HSPCs co-cultured with NK/Tp cells of HC and ITP, respectively. Two-tailed Student’s t test; ns, not significant; n = 6

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