Fig. 1
From: Innate immune imprints in SARS-CoV-2 Omicron variant infection convalescents
Schematics of the overall study design and plasma levels of cytokines and chemokines in SARS-CoV-2 Omicron convalescents. a Schematics depicting the overall experimental design of this study. Peripheral blood mononuclear cells (PBMCs) and plasma were collected from SARS-CoV-2 Omicron convalescents and matched healthy controls and then processed to single-cell RNA sequencing (scRNA-seq), surface proteome profiling (Abseq), and cytokine and chemokine assays. b, c Plasma levels of cytokines and chemokines from SARS-CoV-2 Omicron convalescents (n = 143) and healthy controls (n = 48). SARS-CoV-2 Omicron-infected individuals were divided into mild (n = 62) and moderate (n = 81) disease severity groups according to WHO living guidance for clinical management of COVID-19. Twenty-seven cytokines and chemokines were measured by the Bio‐Plex pro human cytokine assays and MAGPIX system (Luminex). Fold change of average plasma concentrations of cytokines and chemokines were shown in (b), and the differences in cytokines and chemokines between mild and moderate convalescents were shown in (c). Statistical significance was determined by two-tailed Mann–Whitney U test
