Fig. 2 | Signal Transduction and Targeted Therapy

Fig. 2

From: Innate immune imprints in SARS-CoV-2 Omicron variant infection convalescents

Fig. 2

The peripheral immune cell profiling of the Omicron variant-infected convalescents and healthy donors. a UMAP plots showing all the 34 cell clusters in peripheral blood from convalescents with mild to moderate Omicron infection and healthy controls. Clusters were named based on the cluster-specific expression patterns at protein and transcript levels, followed by the major cell type. See also Supplementary Fig. S3, S4 and Table. S4. b UMAP plots showing the cell clusters in PBMCs from the Omicron convalescents experienced mild or moderate clinical symptoms and healthy controls. c The composition of monocytes and low-density neutrophils (LDNs) measured by the ratio of observed to randomly expected cell numbers (RO/E) in PBMCs from the Omicron convalescents (n = 7 for mild and n = 16 for moderate) and healthy controls (n = 6). d The composition of monocytes measured by percentages in PBMCs from the Omicron convalescents and healthy controls. t-test with Welch’s correction. e The composition of LDNs measured by percentages in PBMCs from the Omicron convalescents and healthy controls. t-test with Welch’s correction. f The composition of monocytes measured by percentages in PBMCs from the moderate convalescents and healthy controls. t-test with Welch’s correction. g The composition of LDNs measured by percentages in PBMCs from the mild convalescents and healthy controls. t-test with Welch’s correction

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