Fig. 4 | Signal Transduction and Targeted Therapy

Fig. 4

From: Tripterin liposome relieves severe acute respiratory syndrome as a potent COVID-19 treatment

Fig. 4

scRNA-seq analysis of pulmonary cell clusters in treated mice. a Schematic illustration of the treatment strategy, lung dissociation, single-cell preparation, and scRNA-seq sequencing and analysis. b UMAP plot of 28229 cells from Blank, Model, Vehicle lipo, and TP lipo mouse testes. The number of cells in each cluster: Neutrophil (9308), Macrophage (3932), B cell (2977), AM (3592), T cell (3499), DC (2676), Endo cell (1226), NK cell (429), Fibroblast (220), Plasma cell (193), and AT2 (177). c Heatmap of the top transcripts in each cluster showed clear demarcation between different clusters. d UMAP plots showing the dynamic changes in all cell clusters in the lung among each group

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