Table 1 Ribosome-related factors and CVD

rDNA

Cardiomyocyte

p-UBF↑

Promotes cardiac hypertrophy

^{201,202,203,204}

Cardiomyocyte

Ncl↑

Inhibits myocardial infarction

^235,236,237

Cardiomyocyte

Ncl↑

Promotes cardiomyocyte differentiation

^166,169,170

rRNA

Cardiomyocyte

S6K1↑

Promotes cardiac hypertrophy

¹⁶¹

Cardiomyocyte

RNA Pol I↑

Promotes cardiac hypertrophy

¹⁶⁰

Cardiomyocyte

rDNA↑

Promotes cardiac hypertrophy

^151,161

RP

Cardiomyocyte

RPL9/26↓

Promotes myocardial infarction

¹⁶⁸

Macrophages

RPL13↑

Inhibits atherosclerosis

^181,182,183

Blood cells

RPL9/23/35, RPS7↓

Promotes atherosclerosis

¹⁸⁴