Fig. 2 | Signal Transduction and Targeted Therapy

Fig. 2

From: CircRNA DICAR as a novel endogenous regulator for diabetic cardiomyopathy and diabetic pyroptosis of cardiomyocytes

Fig. 2

Effect of DICAR on the cardiac functions and remodeling. a Echocardiography images of DICAR+/− mouse. b Summary of the heart functions, including stroke volume (SV), ejection fraction (EF), left ventricular end-diastolic dimension (LVEDD), cardiac output (CO), fractional shortening (FS). c Representative images and summary data of wheat germ agglutinin (WGA) staining. d Representative images and summary data of Masson staining of DICAR+/−. e Representative IHF images and summary data of collagen III. f Representative and summary data of WB images of pyroptosis detected in the heart tissues. Data are represented as mean ± SEM. *P < 0.05, **P < 0.01 vs. WT group, n = 6–8

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