Fig. 1
From: Osteoarthritis: pathogenic signaling pathways and therapeutic targets
Phenotypes of Osteoarthritis (OA). Clinic evidence shows that the majority of OA patients have a diversity of OA phenotypes, including articular cartilage erosion, synovial hyperplasia, abnormal angiogenesis, synovial inflammation, subchondral bone disturbance, ligaments and tendons instability, and joint stiffness. Left-half side shows the structure of the normal synovial joint. Right-half side showed the possible alterations of synovial joint structure and symptoms in osteoarthritis
