Table 4 Regulation of circRNA in metabolic disease
From: Epigenetic regulation in metabolic diseases: mechanisms and advances in clinical study
Diseases | Major regulator | Target gene | Effect | References |
|---|---|---|---|---|
T2D | circ_0071336 | miR-93-5p | ↑ | |
T1D | circPPM1F | HuR, FUS, EIF4A3 | ↑ | |
GDM | circMAP3K4 | miR-6795-5p | ↑ | |
DR | circNNT | miR-320b | ↓ | |
DC | circHIPK3 | PTEN | ↓ | |
diabetic wounds healing | circARHGAP12 | miR-301b-3p | ↑ | |
Obesity | circSAMD4A | miR-138-5p | ↓ | |
Obesity | circFLT1 | miR-93 | ↓ | |
Obesity | circPPARγ | miR-92a-3p | ↓ | |
Obesity | circFUT10 | let-7c | ↑ | |
Obesity | circOgdh | miR-34a-5p | ↓ | |
Obesity | circARF3 | miR-103 | ↓ | |
NAFLD | circRNA_0001805 | miR-106a-5p, miR-320a | ↓ | |
NAFLD | circ_0057558 | miR-206 | ↑ | |
NAFLD | circ_0048179 | miR-188-3p | ↓ | |
NAFLD | circRNA SCAR | PGC-1α | ↓ | |
NAFLD | circRNA_002581 | miR-122 | ↓ | |
Osteoporosis | circIGSF11 | miR-199b-5p | ↓ | |
Osteoporosis | circ_0074834 | miR-942-5p | ↓ | |
Osteoporosis | circRNA_0016624 | miR-98 | ↓ | |
Osteoporosis | circRNA_0048211 | miR-93-5p | ↓ | |
Osteoporosis | circStag1 | HuR | ↓ | |
Osteoporosis | circRNA AFF4 | miR-7223-5p | ↓ | |
Osteoporosis | circHIPK3 | miR-124 | ↓ | |
Osteoporosis | circRNA_28313 | miR-195a | ↑ | |
Osteoporosis | circBBS9 | miR-423-3p | ↓ |
