Table 1 The EC50 (μM, mean ± sd) of the drugs against different SARS-CoV-2 mutants

From: Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2

Drugs

Cell Lines

Wild Type

Delta

Omicron

Nelfinavir

Vero E6

2.93 ± 0.32

2.09 ± 0.23

2.03 ± 0.12

Nelfinavir

Calu-3

1.86 ± 0.26

1.76 ± 0.21

1.73 ± 0.08

Remdesivir

Vero E6

1.01 ± 0.13

0.85 ± 0.10

1.50 ± 0.20

Remdesivir

Calu-3

1.11 ± 0.17

1.11 ± 0.12

1.50 ± 0.07

Paxlovid

Vero E6

0.85 ± 0.16

1.22 ± 0.09

1.84 ± 0.05

Paxlovid

Calu-3

1.62 ± 0.2

0.73 ± 0.08

2.48 ± 0.26

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