Fig. 5
From: TET (Ten-eleven translocation) family proteins: structure, biological functions and applications
Primary factors in positive(red) and negative(blue) regulation of TETs activity and the outmost layer described the involved mechanism. FOXA1,201 Vitamin C,238 CRL4(VprBP),224 P300,222 and AMPK223 enhanced TETs activity, while Vpr,227 IDAX,116 Calpain 1,228 2HG232 and miR-29b207 decreased TETs activity
