Fig. 5

Changes of BCAAs and ArAAs in the brain during STF. a Heat map of BCAA and ArAA levels after different periods of fasting in seven brain regions. b Changes of BCAAs/ArAAs ratios after STF in seven brain regions. One-way ANOVA was used to identify differences between different time points in each tissue. c Correlation between metabolites in phase I. d Correlation between metabolites in phase II. Isoleu, isoleucine; Val, valine; Leu, leucine; Tyr, tyrosine; Phe, phenylalanine; Asp, aspartic acid. *0.01 < p < 0.05, **0.001 < p < 0.01, ***p < 0.001