Fig. 6 | Signal Transduction and Targeted Therapy

Fig. 6

From: Immunity-and-matrix-regulatory cells enhance cartilage regeneration for meniscus injuries: a phase I dose-escalation trial

Fig. 6

Clinical trial shows efficacy outcomes of IMRCs in MRI analysis and knee function scores after IMRCs injection. a–c Impairment of meniscus in knee MRI scans in different dose groups. d Percentage of patients with meniscus repair. e The volume analysis of the meniscus at six time points post-injection. f–i The change of knee function scores after IMRCs injection. VAS pain score (f), WOMAC score (g). AKS knee score (h), and Lysholm knee scale (i). VAS, Visual Analogue Score. WOMAC, Western Ontario and McMaster Universities Osteoarthritis Index. AKS, American Knee Society. For (f)–(i), n = 6 in each group. *P < 0.05; Data are presented as mean ± SEM

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