Fig. 12
From: G protein-coupled receptors (GPCRs): advances in structures, mechanisms and drug discovery
11 allosteric binding sites reported across GPCRs mapped onto representative class A GPCR CB1R. Gray pockets represent binding pockets within 7TMD, and white pockets represent binding pockets outside 7TMD. For each pocket, the number of unique ligands is indicated using boldface type, and the number of GPCRs containing the pocket is provided in parentheses. The boundary of the lipid bilayer is indicated by gray dashes
