Table 2 Factors influencing neutralizing and anti-RBD antibody production in the elderly

From: Safety, immunogenicity and protective effect of sequential vaccination with inactivated and recombinant protein COVID-19 vaccine in the elderly: a prospective longitudinal study

Time points

Variables

OR (95% CI)

P value

Neutralizing antibodies

   

 Month 2

Underlying diseases: combine (vs not combine)

0.228 (0.094–0.550)

0.001

 Month 7

Age

0.888 (0.815–0.967)

0.007

 

Underlying diseases: combine (vs not combine)

0.377 (0.167–0.849)

0.019

Anti-RBD antibodies

 Month 2

Gender: female (vs male)

2.576 (1.046–6.342)

0.040

Underlying diseases: combine (vs not combine)

0.361 (0.144–0.903)

0.029

 Month 7

Gender: female (vs male)

2.653 (1.257–5.600)

0.010

Underlying diseases: combine (vs not combine)

0.398 (0.191–0.828)

0.014

  1. Data were analyzed using multivariate logistic regression