Table 1 Participant characteristics

From: Anti-PD-L1 antibody ASC22 in combination with a histone deacetylase inhibitor chidamide as a “shock and kill” strategy for ART-free virological control: a phase II single-arm study

No.

Age (years)

Gender

Ethnicity

BMI (kg /m2)

Months since HIV diagnosis

Days from HIV diagnosis to ART initiation

Months on ARTs

Current ART regimens

Months with HIV RNA < 50 copies/mL

Baseline CD4 counts (cells/μL)

Baseline CD8 counts (cells/μL)

Baseline CD4/CD8 ratios

01

29

Male

Asian

20.6

52.1

0

52.1

ABC, 3TC, DTG

45.3

304

571

0.5

02

28

Male

Asian

19.2

158.1

2570

72.5

TAF, 3TC, DTG

32.8

539

814

0.7

03

53

Male

Asian

28.1

39

19

38.4

ABC, 3TC, DTG

33.4

370

879

0.4

04

25

Male

Asian

21.9

35.9

251

27.6

TDF, 3TC, EFV

21.8

405

670

0.6

05

30

Male

Asian

22.7

57.1

54

55.3

TDF, 3TC, EFV

49.6

433

578

0.8

06

38

Male

Asian

30.0

111

1291

68

TDF, 3TC, EFV

49.2

633

1355

0.5

08

51

Male

Asian

25.1

103.6

197

97

ABC, 3TC, DTG

49.8

902

1462

0.6

09

34

Male

Asian

28.1

57.6

18

57

TAF, FTC, DTG

50.9

785

998

0.8

10

31

Male

Asian

25.0

62.1

26

61.3

TDF, 3TC, LPV/r

30.5

730

1319

0.6

11

33

Male

Asian

22.5

85

1311

41.3

TDF, 3TC, EFV

35.7

844

989

0.9

12

53

Male

Asian

18.4

144.5

23

143.7

TDF, 3TC, EFV

98.4

284

547

0.5

13

42

Male

Asian

26.9

25

0

25

TDF, 3TC, EFV

24.8

670

991

0.7

14

36

Male

Asian

21.7

75.6

41

74.2

TDF, 3TC, EFV

69

398

712

0.6

15

37

Male

Asian

20.7

198.7

735

174.2

AZT, 3TC, EFV

102.9

349

1074

0.3

16

38

Male

Asian

20.8

87.5

163

82.1

TDF, 3TC, EFV

76.3

327

444

0.7

Median (range)

36 (25–53)

  

22.5 (20.7–26.9)

75.6 (25–198.7)

54 (0–2570)

61.3 (25–174.1)

 

49.2 (21.8–102.9)

433 (284–902)

879 (444–1462)

0.6 (0.3–0.9)

  1. Continuous variables are presented as median [interquartile range, (IQR)]
  2. ABC Abacavir, ART antiviral therapy, AZT azidothymidine, BMI body mass index, DTG Dolutegravir, TAF tenofovir alafenamide fumarate, TDF tenofovir disoproxil fumarat, EFV Efavirenz, LPV/r lopinavir/ritonavir, 3TC lamivudine