Fig. 8
Echocardiographic measurements in A17fl/fl and A17α-MHCKO tumor-bearing mice treated with NS or DOX. a Experiment timeline of breast cancer-bearing mice. b Representative anatomical images of tumor size (scale bar = 1 cm) in four groups of mice. c Comparison of tumor volume among four groups of mice (n = 6 in each group). d Comparison of tumor weight among four groups of mice (n = 6 in each group). e Representative echocardiographic images (scale bar = 2 mm) showing B-mode and M-mode echocardiograms in four groups of mice. f Comparison of left ventricular ejection fraction (LVEF) among four groups of mice (n = 6 in each group). g Comparison of left ventricular fractional shortening (LVFS) among four groups of mice (n = 6 in each group). h Experiment timeline of melanoma-bearing mice. i Representative anatomical images of tumor size (scale bar = 1 cm) in four groups of mice. j Comparison of tumor volume among four groups of mice (n = 6 in each group). k Comparison of tumor weight among four groups of mice (n = 6 in each group). l Representative echocardiographic images (scale bar = 2 mm) showing B-mode and M-mode echocardiograms in four groups of mice. m Comparison of left ventricular ejection fraction (LVEF) among four groups of mice (n = 6 in each group). n Comparison of left ventricular fractional shortening (LVFS) among four groups of mice (n = 6 in each group). Values shown were mean and SEM. One-way ANOVA were applied in (c, d, f, g, j, k, m and n). *p < 0.05; **p < 0.01; ***p < 0.001
