Fig. 2
From: Neutralizing antibody responses to three XBB protein vaccines in older adults
Neutralization of the SARS-CoV-2 lineage before and after immunization with three XBB-containing vaccines. a–c Comparison of SARS-CoV-2 lineage-specific neutralization titers against the indicated pseudoviruses before and after trivalent XBB.1.5 vaccine (a), bivalent Omicron XBB vaccine (b), and tetravalent XBB.1 vaccine (c) immunization. Each dot represents the 50% neutralization titer (NT50) for an individual. The horizontal dotted line in the neutralization assay indicates a limit of detection of 30, with serum samples demonstrating neutralization below 30 plotted as 10. The geometric mean titers (GMTs) of the neutralizing antibodies and the percentages of individuals with NT50 values above the limit of detection are indicated below each group. Statistical analyses were performed using a two-tailed Friedman test with a false discovery rate. A p-value <0.05 was considered statistically significant, and only significant differences are displayed in the figure, with the fold change in the GMT denoted in brackets
