Fig. 3
Impacts of vaccine booster and age on neutralization against Omicron sublineages. a Comparison of neutralizing antibody titers against BA.2.75, BF.7, BQ.1, XBB.1.5, XBB.1.9.1, XBB.1.16, XBB.2.3, EG.5.1, BA.2.86 and JN.1 pseudoviruses in sera from individuals with or without a WSK-V102C booster in the past year. Among all the 49 individuals, 26 participants did not receive a vaccine booster for more than one year, while 23 of them received a dose of WSK-V102C booster in the period around February 2023. b Comparison of neutralization against Omicron sublineage pseudoviruses by sera from participants who received 1 ~ 3 doses (n = 37) and 4 doses (n = 12) of COVID-19 vaccine. c Comparison of neutralization against different Omicron sublineage pseudoviruses by sera from male (n = 16) and female (n = 33) participants. Data are presented as geometric mean values ± SD in (a–c). Unpaired Student’s t-tests were performed. Statistical significance is indicated by *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns not significant
