Fig. 6 | Signal Transduction and Targeted Therapy

Fig. 6

From: Neuron-targeted caveolin-1 overexpression attenuates cognitive loss and pathological transcriptome changes in symptomatic Alzheimer’s disease models

Fig. 6The alternative text for this image may have been generated using AI.

SynCav1 maintains hippocampal ADNP expression in PSAPP and APPKI mice. a, b IB of hippocampal homogenates for ADNP, Cav-1, and Fl-APP for PSAPP mice and quantification. n = 6–8. c–e IB of hippocampal homogenates for ADNP, Cav-1, and Fl-APP for male (n = 6–8) and female (n = 9–10) APPKI mice with quantification. Data are presented as mean ± SEM and analyzed using One-way ANOVA or Student’s t test within each sex. Significance was assumed when p < 0.05. *p < 0.05, **p < 0.01, ***p < 0.005, ****p < 0.0001

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