Fig. 4

Nomogram and calibration curve of differentiation syndrome. a The nomogram integrates key clinical variables to estimate the probability of differentiation syndrome. Each variable is assigned a point value on the upper scale (e.g., 15 for WBC_base and 25 for HB_base). The total score, derived from summing up the points for all variables (e.g., a cumulative score of 309.5), is then referenced on the lower axis to determine the corresponding predicted probability (e.g., approximately 50% risk in this instance). b The calibration curve evaluates the agreement between predicted and observed probabilities. The apparent line (blue dashed) represents uncorrected predictions, the bias corrected line (yellow dashed) shows adjusted predictions, and the ideal line (gray dashed) indicates perfect calibration. WBC white blood cell, HB hemoglobin, PLT platelet