Table 1 Basic information on enrolled patients

From: A multicenter single-arm clinical study of Chinese children’s cancer group-acute promyelocytic leukemia-2017 (CCCG-APL-2017) protocol

Characteristics

LR

HR

p value

n

117

82

 

Gender, n (%)

  

0.91

 Female

49 (41.9%)

35 (42.7%)

 

 Male

68 (58.1%)

47 (57.3%)

 

Age (year), median (IQR)

9 (7, 11)

10 (6.25, 12)

0.38

WBC (×109L), median (IQR)

2.8 (1.83, 4.54)

23.17 (13.57, 54.29)

<0.001

HB (g/L), mean±SD

81.97 ± 20.86

76.51 ± 22.99

0.08

PLT (×109L), median (IQR)

33 (18, 58)

37 (16, 58.5)

0.94

Proportion of naive cells in peripheral blood (%), median (IQR)

15 (3, 42)

69.5 (40, 84)

<0.001

Fever, n (%)

  

0.09

 yes

77 (65.8%)

63 (76.8%)

 

 no

40 (34.2%)

19 (23.2%)

 

Hemorrhage, n (%)

  

0.13

 no

37 (31.6%)

18 (22.0%)

 

 yes

80 (68.4%)

64 (78.0%)

 

Arthralgia, n (%)

  

0.60

 no

106 (90.6%)

76 (92.7%)

 

 yes

11 (9.4%)

6 (7.3%)

 

Central nervous system leukemia, n (%)

  

0.47

 yes

1 (0.9%)

1 (1.2%)

 

 no

116 (99.1%)

80 (97.6%)

 

 UN

0 (0.0%)

1 (1.2%)

 

Family history of tumors or Blood disorders, n (%)

  

0.99

 no

113 (96.6%)

80 (97.6%)

 

 yes

4 (3.4%)

2 (2.4%)

 

Karyotype, n (%)

  

0.70

 no

5 (4.3%)

2 (2.4%)

 

 yes

112 (95.7%)

80 (97.6%)

 
  1. HR high-risk, LR low-risk, WBC white blood cell, HB hemoglobin, PLT platelet, IQR interquartile range (Q1, Q3), SD standard deviation, UN uncertainty