Fig. 1 | Signal Transduction and Targeted Therapy

Fig. 1

From: Ultrasound activated herbal bio-heterojunctions for self-catalytic regulation and bacterial cuproptosis-like death in the treatment of implant infection

Fig. 1

Schematic of the synthesis and IAI Treatment. a Schematic of the synthetic of Pp-bioHJs. b Schematic depicting the antibacterial strategy of Pp-bioHJs for IAI therapy. The treatment enhances bacterial killing by ultrasound-triggered ROS generation from HB-bioHJs and intracellular Cu(I) overload–induced cuproptosis-like death. The bone scaffold exhibited anti-inflammation, immunoregulation, and osteogenic via Cu(II)-Cur-activated self-catalysis regulation and Sr-mediated treatment in an infected bone implant model

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