Fig. 9 | Signal Transduction and Targeted Therapy

Fig. 9

From: Ultrasound activated herbal bio-heterojunctions for self-catalytic regulation and bacterial cuproptosis-like death in the treatment of implant infection

Fig. 9

In vivo bone regeneration (a, b) 3D micro-CT reconstructions of new bone at weeks 4 (a) and 8 (b) via IMARIS. b, c New bone labeled by calcitonin (green) and alizarin red (red). d, e, f, g Quantification of Tb.Sp (d), Tb.N (e), BV/TV (f), and Tb.Th (g). h Quantification of the MAR. d–g n = 4 biologically independent samples (4 W), n = 6 biologically independent samples (8 W); h n = 3 biologically independent samples. The significance of biologically independent samples was calculated via ANOVA followed by Tukey’s multiple comparisons test. The data are presented as means ± SDs. Significant differences between groups are indicated as *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, and ns: not significance

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