Table 2 Confirmed antitumor activity after conversion therapy

From: Lenvatinib plus transarterial chemoembolization and PD-1 inhibitors as conversion therapies for unresectable intermediate-advanced hepatocellular carcinoma: a phase 2 trial and exploratory biomolecular study

 

RECIST 1.1

mRECIST

Variable

LENTAP

TACE

P value

LENTAP

TACE

P value

Objective response

27 (38.0)

5 (7.0)

<0.001

56 (78.9)

12 (16.9)

<0.001

Complete response

1 (1.4)

0 (0)

 

13 (18.3)

0 (0)

 

Partial response

26 (36.6)

5 (7.0)

 

43 (60.6)

12 (16.9)

 

Stable disease

39 (54.9)

27 (38.0)

 

11 (15.5)

21 (29.6)

 

Disease control

66 (92.9)

32 (45.1)

<0.001

67 (94.4)

33 (45.5)

<0.001

Progressive disease

5 (7.0)

39 (54.9)

 

4 (5.6)

38 (53.5)

 

Amenable for salvage resection

58

21

<0.001

62

25

<0.001

  1. RECIST response evaluation criteria in solid tumors, mRECIST modified RECIST